how can i Grey matter extraction with these algorithm:Filling the holes& Erosion for volume percentage?

in my case in a brain mri image To extract an informative part of grey matter, the fill-hole algorithm is applied first to brain volumes because in some cases WMH are found on gap edges. Then, i want to apply a special algorithm of volume/percentage, in order to eliminate a percentage of the volume external to the brain. please Guide me!

[Image Analyst]

Why do you want to do that? And what does "eliminate" mean to you, keeping in mind that images must remain rectangular and can't have missing pixels. A pixel needs to be there and have a value, though you can set it to zero or some other value if you want to.

[mari ahmad]

Dear Image Analyst! i have a labeled image like this.first i want to skull strip it with this way:1-count the object 2-store labeles 3-determine the volume of each object 4-the greatest volumes are selected and the small volumes are eliminated so as a result, the image of two brain lobes is obtained.i saw the site(part skull stripping) but cant do it can you help me in code or a way that solve my probelems?

[mari ahmad]

afer that,because i just want to segment white matter hyper-intensities(WMH) and grey matter hyper-intensities(GMH) can be confused with the WMH i need to Grey matter extraction in two stage:1-the fill-hole algorithm is applied 2- apply a special algorithm of volume/percentage(( (1) Calculate the volume of non-zero voxels V0 in image fh(x, y)( image from fill-hole algorithm). (2) Assign the input image as the eroded one, fe(x, y) and erode it with the circular structuring element of 3 voxels diametre. (3) Calculate the volume Ve of non-zero voxels in image fe(x, y). (4) Compare V0 and Ve. If (V0 Ve/V0) 100% < 35.55%, then return to step 2. please if possibel help me or say which part of ,matlab help, can help me or which order of matlab i should read? thanks alot.

[Qvna Lhyvnav]

Hey, did you already get the result?