Main Content

Import Data

Import, visualize, and preprocess experimental data, including Excel, CSV, SAS XPORT, and NONMEM

Import tabular data from files to estimate model parameters. Supported file types include Excel®, text, SAS® XPORT, and NONMEM®-formatted files. Visualize and categorize the data in the SimBiology Model Analyzer app or at the command line. Use the time course data of measured drug concentrations to perform noncompartmental analysis (NCA) and calculate PK parameters.

Apps

SimBiology Model BuilderBuild QSP, PK/PD, and mechanistic systems biology models interactively
SimBiology Model AnalyzerAnalyze QSP, PK/PD, and mechanistic systems biology models

Functions

groupedData2tableConvert groupedData object to table
sbioncaCompute noncompartmental analysis (NCA) parameters (requires Statistics and Machine Learning Toolbox)
sbioncaoptionsSpecify options to calculate noncompartmental analysis (NCA) parameters
sbionmimportImport NONMEM-formatted data
sbionmfiledefNONMEM file definition object for sbionmimport
sbiotrellisPlot data or simulation results in trellis plot
sbioplotPlot simulation results in one figure
sbiosubplotPlot simulation results in subplots

Objects

groupedData Table-like collection of data and metadata
SimDataSimulation data

Examples and How To

App Workflow

Calculate NCA Parameters and Fit Model to PK/PD Data Using SimBiology Model Analyzer App

Perform noncompartmental analysis and calibrate model parameters by fitting to experimental PKPD data using nonlinear regression.

Programmatic Workflow

Importing Data

SimBiology lets you import tabular data from external sources programmatically.

Concepts

Importing Data — Supported Files and Data Types

SimBiology lets you import external data saved in several file formats, such as Excel files, text files, and NONMEM-formatted files.

Noncompartmental Analysis

NCA (noncompartmental analysis) lets you calculate pharmacokinetic parameters of a drug without requiring the assumption of a compartmental model.