is 'complete_mednode_dataset' a directory with images in it? Your added code will try to read image files from that path.
Or is 'complete_mednode_dataset' your .mat file? You will have to use a command like load to bring the variables into your workspace. Those variables will not be image files. They may be image data which can be written to an image file using imwrite
I'm still uncertain how you want to use .mat files.
It seems you have no .mat files that already exist, so I assume you want to save some of your variables into a .mat file? For example. to save the variable that is created by your call to imageDatastore, use
save( 'savedimds.mat', 'imds');
or to save several variables, keep adding their names to the end of the command, for example
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