What is the meaning of "global" in matlab GUI?

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What is the purpose of using these global function? Why I have to use this?
function testGUI_OpeningFcn(hObject, eventdata, handles, varargin)
handles.output = hObject;
% guidata(hObject, handles);
% set(findall(handles.uipanel1,'-property','enable'),'enable','on');
% set(handles.uipanel1,'visible','on');
% set(findall(handles.uipanel6,'-property','enable'),'enable','off');
% set(handles.uipanel6,'visible','off');
% set(findall(handles.uipanel7,'-property','enable'),'enable','off');
% set(handles.uipanel7,'visible','off');
global setting
global List
global i
set(handles.text27,'String','Welcome to Music Listening Test');
Stephen23 on 13 Aug 2020
Edited: Stephen23 on 13 Aug 2020
"Why I have to use this?"
You don't have to.
Using global variables makes accessing variables slow, liable to bugs, and difficult to debug.
The MATLAB documentation lists the recommended ways of passing data within a GUI:
The MATLAB documentation also advises "Use global variables sparingly, if at all."

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