A quantitative systems pharmacology (QSP) modeling platform for immuno‐oncology (IO) that incorporates detailed mechanisms for important immune interactions. This modular platform allows for the construction of QSP models of IO with varying degrees of complexity based on specific research questions.
An in-depth tutorial has been published in CPT:PSP (doi: 10.1002/psp4.12546).
Richard Sove (2021). QSPIO (https://github.com/popellab/qspio/releases/tag/v1.0), GitHub. Retrieved .
Sové, Richard J., et al. “QSP-IO: A Quantitative Systems Pharmacology Toolbox for Mechanistic Multiscale Modeling for Immuno-Oncology Applications.” CPT: Pharmacometrics & Systems Pharmacology, vol. 9, no. 9, Wiley, Sept. 2020, pp. 484–97, doi:10.1002/psp4.12546.
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