Let us assume that  and re-write the problem as follows:
 and re-write the problem as follows: 
Let's transform it so it can be used in an ode setting:
These are used in the function (vdp1) as follows:
solve this the time interval of [0 10] with initial values of [0.2 0] for x_1, x_2 respectively.
[t,x] = ode45(@vdp1,[0 10],[0.2 0])
t = 
         0
    0.0001
    0.0003
    0.0004
    0.0005
    0.0011
    0.0018
    0.0024
    0.0030
    0.0062
x = 
    0.2000         0
    0.2000   -0.0001
    0.2000   -0.0001
    0.2000   -0.0002
    0.2000   -0.0002
    0.2000   -0.0005
    0.2000   -0.0007
    0.2000   -0.0010
    0.2000   -0.0012
    0.2000   -0.0024
plot(t,x(:,1),'-o',t,x(:,2),'-o')
title('Solution with ODE45');
function dxdt = vdp1(t,x)
dxdt = [x(2); -2*(x(2)+x(1))];