T-Test with covariates?

Hello MATLAB Experts,

I am trying to run a T-TEST between 2 groups, while taking into account age and gender as nuisance covariates. How can I go about doing that?

Thanks.

Answer 1

[Anton Semechko]

In medical image processing application general linear model is often used to test null-hypotheses while accounting for covariates like age and gender. The idea there is fit linear multiple regression model to data, and then only perform t-tests on regression coefficients corresponding to the variables of interest.