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"simulations failed when using the initial values of estimated parameters" with simbiology fitting but no error when using the same parameters/setting for sbiosimulate
It's difficult to diagnose without more information. Can you share your code either here on MATLAB Answers or privately with the...
8 days ago | 0
Using multiple datasets to fit parameters simultaneously in SimBiology
You first need to decide whether these two concentration profiles should be treated as part of the same experiment/simulation. ...
11 days ago | 1
| accepted
Using multiple datasets to fit parameters simultaneously in SimBiology
SimBiology users typically do this by merging the multiple datasets into a single dataset and fitting them constructing an apprp...
12 days ago | 0
How to add digestibility in SimBiology Model Builder
I'm not sure what you mean by digestibility. The closest I know of is this SimBiology example, which implements a couple of reac...
23 days ago | 0
Model reduction of simbiology models
Hi Paulo, The model order reduction functionality that you point to is limited to linear time-invariant systems. Most SimBiolog...
26 days ago | 0
| accepted
How to download old version of toolbox?
I think the versions you are allowed to download depend on your license. If you go to https://www.mathworks.com/downloads/ , the...
1 month ago | 1
| accepted
simFunction and dose Array from an input file
Ok, I think I finally understand what's going on. When you create the SimFunction, you only need to specify one "template" dose...
2 months ago | 0
| accepted
Simbiology Model Analyzer: input error for CMAX and Partial AUC
Hi, This is a bug. The bug is triggered if you try to calculate partial areas and some of the subjects don't have enough measur...
3 months ago | 1
| accepted
Jump species quantity then stay constant
I don't yet understand what your goal is. Can you provide more details on what behavior you want? A concrete example illustratin...
4 months ago | 1
how to understand and set the constant and boundarycondition properties.
If the Constant property of a species is true, then the value of that species cannot change at simulation times > 0. At time = 0...
5 months ago | 0
Unit conversion in Simbiology model
Hi, I'm a developer on the SimBiology team. I'm not sure I fully understand your question, but I'll try to answer based on my cu...
6 months ago | 0
| accepted
How to find the sensitivity of the model output if it is a variable for repeated assignment?
The solution I generally recommend is to calculate the sensitivities yourself by manualy differentiating the repeated assignment...
6 months ago | 0
how to handle the error 'Levenberg-Marquardt algorithm the Jacobian at BETA0 is ill-conditioned'?
It's difficult to say exactly what's going on without seeing your model and data. One explanation is that your model is not appr...
6 months ago | 0
How to write code for repetitive process?
If I understand your question, you're asking how to create an event that fires repeatedly. I'm not sure exactly what kind of rep...
6 months ago | 0
Investigating the effect of two covariates to an estimated parameter
Yes, you can specify multiple covariates. An example covariate expresssion would be exp(theta_fixed + theta1*covariate1 + theta2...
6 months ago | 0
| accepted
Why are population estimated parameters values the same as individual estimated parameters values?
Without the actual project, it's difficult to say what's going on. So let me offer some potential explanations for what you're s...
6 months ago | 0
How to simulate a drug concentration-time curve with confidence intervals?
Where did this plot come from? Without more information, we won't be able to say exactly how it was created. However, it looks ...
6 months ago | 0
| accepted
Oral Dose Not Exhibiting Absorption/Bioavailability in Simulation
Copying the answer from the comments: "Just wanted to update that I figured out a solution to the problem! I ended up creating a...
7 months ago | 0
Simbiology Previous Initial Parameters
The results of a fit only contain the outputs of the fit itself (for example, parameter estimates). If you want to reproduce tho...
8 months ago | 0
Transfer parameter estimates to model
For item #1, the SimBiologyModelAnalyzer app allows you to create a variant of the parameter estimates (see here for more detail...
8 months ago | 2
| accepted
Encoding conditional assignments in SimBiology
Hi emjey, I see this problem solved in one of two ways: 1) Take advantage of true/false getting converted to 1/0 in mathematic...
8 months ago | 1
How do I fit multiple curves at once, sharing some fitting parameters and floating others?
Are the 6 different analyte concentrations something you want to specify or estimate? Both of these these are possible in SimBio...
9 months ago | 1
| accepted
Different dilution effect on the kinetics of a time course
Hi Luis, Because you don't use units in your model, SimBiology interprets the reaction rates to have dimensions of amount/time....
9 months ago | 0
| accepted
Question re/ matlab.codetools.requiredFilesAndProducts function.
I'd first check the "Certain" field of the pList output to see if these products have been marked as definitely or just possibly...
10 months ago | 0
changes the the simulated mass with changing the absolute and relative tolerance
First, a disclaimer. I'm a SimBiology developer, not a modeler. So I'm most knowledgable about what is technically possible with...
10 months ago | 0
different event functions for the same species
The problem is that you have two conflicting mathematical definitions of Fw. You are trying to set it with both a repeated assig...
11 months ago | 0
| accepted
How do I fix a duplicate name error ?
It's hard to know exactly what's going on without more details. Can you share more details? Ideally, can you share the project a...
11 months ago | 0
| accepted
A variable is specified by more than one assignment rule
It sounds like you have an ill-defined problem with an algebraic loop. Specifically, A_Total is a function of a, but a is a func...
11 months ago | 0
Data fit to observables
Hi Justine, I just tried this in R2023b, and I was able to select an observable in the mapping for the response. I'm attaching ...
12 months ago | 0
| accepted
Fitting model on a Debian machine
If you want to fit a SimBiology model using a command-line function, you can directly call sbiofit (or sbiofitmixed). This is ex...
12 months ago | 0
